Leighl, Natasha B. : rechercher sur Z-Library

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1

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

Garon, Edward B., Rizvi, Naiyer A., Hui, Rina, Leighl, Natasha, Balmanoukian, Ani S., Eder, Joseph Paul, Patnaik, Amita, Aggarwal, Charu, Gubens, Matthew, Horn, Leora, Carcereny, Enric, Ahn, Myung-Ju,

Journal:

New England Journal of Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 974 KB

english, 2015

2

Hyperprogressive disease in early-phase immunotherapy trials: Clinical predictors and association with immune-related toxicities

Kanjanapan, Yada, Day, Daphne, Wang, Lisa, Al-Sawaihey, Hamad, Abbas, Engy, Namini, Amirali, Siu, Lillian L., Hansen, Aaron, Razak, Albiruni Abdul, Spreafico, Anna, Leighl, Natasha, Joshua, Anthony M.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 459 KB

english, 2019

3

The role of cytology in molecular testing and personalized medicine in lung cancer: A clinical perspective

Young, Kelvin, da Cunha Santos, Gilda, Card, Paul, Leighl, Natasha

Journal:

Cancer Cytopathology

Année:

2018

Langue:

english

Fichier:

PDF, 183 KB

english, 2018

4

Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study

Garon, Edward B., Hellmann, Matthew D., Rizvi, Naiyer A., Carcereny, Enric, Leighl, Natasha B., Ahn, Myung-Ju, Eder, Joseph Paul, Balmanoukian, Ani S., Aggarwal, Charu, Horn, Leora, Patnaik, Amita, Gu

Journal:

Journal of Clinical Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 797 KB

english, 2019

5

Death anxiety in patients with metastatic non-small cell lung cancer with and without brain metastases

Eggen, Annemarie C., Reyners, Anna K.L., Shen, Gerald, Bosma, Ingeborg, Jalving, Mathilde, Leighl, Natasha B., Liu, Geoffrey, Richard, Nadine M., Mah, Kenneth, Shultz, David B., Edelstein, Kim, Rodin,

Journal:

Journal of Pain and Symptom Management

Année:

2020

Fichier:

PDF, 963 KB

2020

6

Mechanisms of osimertinib resistance and emerging treatment options

Schmid, Sabine, Li, Janice J.N., Leighl, Natasha B.

Journal:

Année:

2020

Fichier:

PDF, 1.10 MB

2020

7

Determinants of quality of life in patients with advanced cancer

Camilla Zimmermann, Debika Burman, Nadia Swami, Monika K. Krzyzanowska, Natasha Leighl, Malcolm Moore, Gary Rodin, Ian Tannock

Journal:

Supportive Care in Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 164 KB

english, 2011

8

Development and evaluation of a decision aid for patients considering first-line chemotherapy for metastatic breast cancer

Kimberly S. Chiew, Heather Shepherd, Janette Vardy, Martin H.N. Tattersall, Phyllis N. Butow, Natasha B. Leighl

Journal:

Health Expectations

Année:

2008

Langue:

english

Fichier:

PDF, 430 KB

english, 2008

9

Clinical Outcomes of Extensive Stage Small Cell Lung Carcinoma Patients Treated With Consolidative Thoracic Radiotherapy

Meredith E. Giuliani, Soha Atallah, Alexander Sun, Andrea Bezjak, Lisa W. Le, Anthony Brade, John Cho, Natasha B. Leighl, Frances A. Shepherd, Andrew J. Hope

Journal:

Clinical Lung Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 331 KB

english, 2011

10

The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer

Peters, Solange, Bexelius, Christin, Munk, Veronica, Leighl, Natasha

Journal:

Cancer Treatment Reviews

Année:

2016

Langue:

english

Fichier:

PDF, 480 KB

english, 2016

11

Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non–Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

Leighl, Natasha B., Rizvi, Naiyer A., de Lima, Lopes Gilberto, Arpornwirat, Wichit, Rudin, Charles M., Chiappori, Alberto A., Ahn, Myung-Ju, Chow, Laura Q.M., Bazhenova, Lyudmila, Dechaphunkul, Arunee

Journal:

Clinical Lung Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 507 KB

english, 2016

12

P2.39: Long-Term OS for Patients With Advanced NSCLC Enrolled in the KEYNOTE-001 Study of Pembrolizumab

Ramalingam, Suresh, Hui, Rina, Gandhi, Leena, Carcereny, Enric, Felip, Enriqueta, Ahn, Myung-Ju, Eder, Joseph P., Balmanoukian, Ani S., Leighl, Natasha, Aggarwal, Charu, Horn, Leora, Patnaik, Amita, M

Journal:

Journal of Thoracic Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 106 KB

english, 2016

13

Systemic Therapy of Lung Cancer CNS Metastases Using Molecularly Targeted Agents and Immune Checkpoint Inhibitors

O’Kane, Grainne M., Leighl, Natasha B.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 576 KB

english, 2018

14

Rationale and Protocol for a Canadian Multicenter Phase II Randomized Trial Assessing Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non–small-cell Lung Cancer (NCT02788461)

Raman, Srinivas, Bissonnette, Jean-Pierre, Warner, Andrew, Le, Lisa, Bratman, Scott, Leighl, Natasha, Bezjak, Andrea, Palma, David, Schellenberg, Devin, Sun, Alexander

Journal:

Clinical Lung Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 524 KB

english, 2018

15

Economic analysis of osimertinib in previously untreated EGFR-mutant advanced non-small cell lung cancer in Canada

Ezeife, Doreen A., Kirk, Veronica, Chew, Derek S., Nixon, Nancy A., Lee, Roy, Le, Lisa W., Chan, Kelvin K.-W., Leighl, Natasha B.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2018

16

The Role of Angiogenesis Inhibitors in the Era of Immune Checkpoint Inhibitors and Targeted Therapy in Metastatic Non-Small Cell Lung Cancer

Perdrizet, Kirstin, Leighl, Natasha B.

Journal:

Current Treatment Options in Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2019

17

Improving lung cancer diagnosis: the evolving role of patients and care providers

Sung, Mike R., Leighl, Natasha B.

Journal:

Journal of Thoracic Disease

Année:

2019

Langue:

english

Fichier:

PDF, 118 KB

english, 2019

18

Emerging therapies for non-small cell lung cancer

Zhang, Chao, Leighl, Natasha B., Wu, Yi-Long, Zhong, Wen-Zhao

Journal:

Journal of Hematology & Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2019

19

Immune Checkpoint-Inhibitors and Chemoradiation in Stage III Unresectable Non-Small Cell Lung Cancer

Melosky, Barbara, Juergens, Rosalyn, McLeod, Deanna, Leighl, Natasha, Brade, Anthony, Card, Paul B., Chu, Quincy

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 719 KB

english, 2019

20

RADI-08. A SURVEY BASED STUDY OF BRAIN METASTASES MANAGEMENT FOR PATIENTS WITH NON-SMALL CELL LUNG CANCERS OR MELANOMA

Fong, Chin Heng, Leighl, Natasha, Butler, Marcus, Doherty, Mark, Kruser, Timothy, Shultz, David

Journal:

Neuro-Oncology Advances

Année:

2019

Fichier:

PDF, 137 KB

2019

21

Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline

Schneider, Bryan J., Ismaila, Nofisat, Aerts, Joachim, Chiles, Caroline, Daly, Megan E., Detterbeck, Frank C., Hearn, Jason W.D., Katz, Sharyn I., Leighl, Natasha B., Levy, Benjamin, Meyers, Bryan, Mu

Journal:

Journal of Clinical Oncology

Année:

2019

Fichier:

PDF, 583 KB

2019

22

Development of the Functional Assessment of Cancer Therapy–Immune Checkpoint Modulator (FACT‐ICM): A toxicity subscale to measure quality of life in patients with cancer who are treated with ICMs

Hansen, Aaron R., Ala‐Leppilampi, Kari, McKillop, Chris, Siu, Lillian L., Bedard, Philippe L., Abdul Razak, Albiruni R., Spreafico, Anna, Sridhar, Srikala S., Leighl, Natasha, Butler, Marcus O., Hogg,

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 244 KB

english, 2020

23

Advancing the systemic therapy of lung cancer: quality or quantity?

Fung, Andrea S, Leighl, Natasha B

Journal:

The Lancet Oncology

Année:

2020

Fichier:

PDF, 138 KB

2020

24

Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study

Tan, Daniel S-W, Leighl, Natasha B, Riely, Gregory J, Yang, James C-H, Sequist, Lecia V, Wolf, Juergen, Seto, Takashi, Felip, Enriqueta, Aix, Santiago P, Jonnaert, Maud, Pan, Chun, Tan, Eugene Y, Ko,

Journal:

The Lancet Respiratory Medicine

Année:

2020

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2020

25

Molecular testing for lung adenocarcinoma: Is it time to adopt a âplasmaâfirstâ approach?

Makarem, Maisam, Leighl, Natasha B.

Journal:

Année:

2020

Fichier:

PDF, 134 KB

2020

26

Multicenter Validation Study to Implement Plasma Epidermal Growth Factor Receptor T790M Testing in Clinical Laboratories

Leighl, Natasha B., Kamel-Reid, Suzanne, Cheema, Parneet K., Laskin, Janessa, Karsan, Aly, Zhang, Tong, Stockley, Tracy, Barnes, Tristan A., Tudor, Roxana A., Liu, Geoffrey, Owen, Scott, Rothenstein,

Journal:

JCO Precision Oncology

Année:

2020

Fichier:

PDF, 672 KB

2020

27

Correlation of immune-related adverse events and response from immune checkpoint inhibitors in patients with advanced non-small cell lung cancer

Sung, Mike, Zer, Alona, Walia, Preet, Khoja, Leila, Maganti, Manjula, Labbe, Catherine, Shepherd, Frances A., Bradbury, Penelope A., Liu, Geoffrey, Leighl, Natasha B.

Journal:

Journal of Thoracic Disease

Année:

2020

Fichier:

PDF, 257 KB

2020

28

Metabolites as Prognostic Markers for Metastatic Non-Small Cell Lung Cancer (NSCLC) Patients Treated with First-Line Platinum-Doublet Chemotherapy

Hao, DesirÃ©e, Sengupta, Arjun, Ding, Keyue, Ubeydullah, ER, Krishnaiah, Saikumari, Leighl, Natasha B., Shepherd, Frances A., Seymour, Lesley, Weljie, Aalim

Journal:

Année:

2020

Fichier:

PDF, 1.46 MB

2020

29

Can Oncologists Predict the Efficacy of Treatments in Randomized Trials?

Benjamin, Daniel M., Mandel, David R., Barnes, Tristan, Krzyzanowska, Monika K., Leighl, Natasha, Tannock, Ian F., Kimmelman, Jonathan

Journal:

Année:

2020

Fichier:

PDF, 452 KB

2020

30

Venous thromboembolism and nonsmall cell lung cancer : A pooled analysis of National Cancer Institute of Canada Clinical Trials Group trials

Lisa K. Hicks, Matthew C. Cheung, Keyue Ding, Baktiar Hasan, Lesley Seymour, Aurélie Le Maître, Natasha B. Leighl, Frances A. Shepherd

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 174 KB

english, 2009

31

Utilization of prophylactic cranial irradiation in patients with limited stage small cell lung carcinoma

Meredith Giuliani, Alexander Sun, Andrea Bezjak, Clement Ma, Lisa W. Le, Anthony Brade, John Cho, Natasha B. Leighl, Frances A. Shepherd, Andrew J. Hope

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 165 KB

english, 2010

32

EGFR gene status in cytological samples of nonsmall cell lung carcinoma : Controversies and opportunities

Gilda da Cunha Santos, Mauro Ajaj Saieg, William Geddie, Natasha Leighl

Journal:

Cancer Cytopathology

Année:

2011

Langue:

english

Fichier:

PDF, 319 KB

english, 2011

33

Phase I Trial of Radiation With Concurrent and Consolidation Pemetrexed and Cisplatin in Patients With Unresectable Stage IIIA/B Non–Small-Cell Lung Cancer

Anthony Brade, Andrea Bezjak, Robert MacRae, Scott Laurie, Alex Sun, John Cho, Natasha Leighl, Shannon Pearson, Bernadette Southwood, Lisa Wang, Shauna McGill, Neill Iscoe, Frances A. Shepherd

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2011

Langue:

english

Fichier:

PDF, 104 KB

english, 2011

34

Determination of GTI-2040, a novel antisense oligonucleotide, in human plasma by using HPLC combined with solid phase and liquid–liquid extractions

Wenjiang Zhang, Natasha Leighl, Diane Zawisza, Malcolm J. Moore, Eric X. Chen

Journal:

Journal of Chromatography B

Année:

2005

Langue:

english

Fichier:

PDF, 126 KB

english, 2005

35

A phase I pharmacokinetic study of bexarotene with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

Heather A. Wakelee, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Desiree Hao, Arturo Lopez-Anaya, Petr Zatloukal, Charlotte D. Jacobs

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 284 KB

english, 2012

36

The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer

Heather A. Wakelee, Chris H. Takimoto, Arturo Lopez-Anaya, Quincy Chu, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Eric K. Rowinsky, Desiree Hao, Petr Zatloukal, Charlotte D. Jacobs,

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 393 KB

english, 2012

37

Enhancing decision making about participation in cancer clinical trials: development of a question prompt list

Richard F. Brown, Elyse Shuk, Natasha Leighl, Phyllis Butow, Jamie Ostroff, Shawna Edgerson, Martin Tattersall

Journal:

Supportive Care in Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 212 KB

english, 2011

38

A Phase 2 study of perifosine in advanced or metastatic breast cancer

Natasha B. Leighl, Susan Dent, Mark Clemons, Theodore A. Vandenberg, Richard Tozer, David G. Warr, R. Michael Crump, David Hedley, Gregory R. Pond, Janet E. Dancey, Malcolm J. Moore

Journal:

Breast Cancer Research and Treatment

Année:

2008

Langue:

english

Fichier:

PDF, 203 KB

english, 2008

39

How Affordable are Targeted Therapies in Non-Small Cell Lung Cancer?

Linda E. Coate, Natasha B. Leighl

Journal:

Current Treatment Options in Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 192 KB

english, 2011

40

Differential Role of Estrogen Receptor Beta in Early Versus Metastatic Non-small Cell Lung Cancer

Sri Navaratnam, Georgios Skliris, Gefei Qing, Shantanu Banerji, Ketan Badiani, Dongsheng Tu, Penelope A. Bradbury, Natasha B. Leighl, Frances A. Shepherd, Janet Nowatzki, Alain Demers, Leigh Murphy

Journal:

Hormones and Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 275 KB

english, 2012

41

Induction chemoradiotherapy facilitates radical resection of T4 non–small cell lung cancer invading the spine

Masaki Anraku, Thomas K. Waddell, Marc de Perrot, Stephen J. Lewis, Andrew F. Pierre, Gail E. Darling, Michael R. Johnston, Rebecca E. Zener, Yoga R. Rampersaud, Frances A. Shepherd, Natasha Leighl, A

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Année:

2009

Langue:

english

Fichier:

PDF, 273 KB

english, 2009

42

A Phase I Study of Pegylated Liposomal Doxorubicin Hydrochloride (Caelyx™) in Combination with Cyclophosphamide and Vincristine as Second-Line Treatment of Patients with Small-Cell Lung Cancer

Natasha B. Leighl, Ronald L. Burkes, Janet E. Dancey, Pedro G. Lopez, Brian P. Higgins, P.L. David Walde, Leona C. Rudinskas, Yasmin H. Rahim, Angela Rodgers, Gregory R. Pond, Frances A. Shepherd

Journal:

Clinical Lung Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 166 KB

english, 2003

43

Classification and Toxicities of Vascular Disrupting Agents

Arman Hasani, Natasha Leighl

Journal:

Clinical Lung Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 122 KB

english, 2011

44

Locoregional failures following thoracic irradiation in patients with limited-stage small cell lung carcinoma

Meredith E. Giuliani, Patricia E. Lindsay, Alexander Sun, Andrea Bezjak, Lisa W. Le, Anthony Brade, John Cho, Natasha B. Leighl, Frances A. Shepherd, Andrew J. Hope

Journal:

Radiotherapy and Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 485 KB

english, 2012

45

O-63 Brain metastases as the initial site of failure in locally advanced non-small cell lung cancer treated with combined modality therapy: Implications for prophylactic cranial irradiation

Sun, Alexander, Carolan, Hannah, Bezjak, Andrea, Yi, Qi-Long, Shepherd, Francis, Ginsberg, Robert, Kane, Gabrielle, Waldron, John, Leighl, Natasha, Feld, Ron, Burkes, Ron, Payne, David

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 181 KB

english, 2003

46

O-118 Optmizing cancer treatment decision-making: Pilot study of a treatment decision aid in stage IV non-small cell lung cancer

Leighl, Natasha B., Shepherd, Frances A., Zawisza, Dianne, Burkes, Ronald L., Feld, Ronald, Waldron, John, Sun, Alexander, Tattersall, Martin H.N.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 193 KB

english, 2003

47

O-233 Platinum-based versus non-platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC): A meta-analysis of the published literature

D'Addario, Giannicola, Pintillie, Melania, Cerny, Thomas, Feld, Ronald, Leighl, Natasha B., Shepherd, Frances A.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 341 KB

english, 2003

48

Phase II study of pegylated liposomal doxorubicin HCI (caelyx) in combination with cyclophosphamide and vincristine as second-line treatment of patients with small cell lung cancer

Leighl, Natasha B., Goss, Glenwood D., Lopez, Pedro, Burkes, Ronald L., Dancey, Janet E., Rahim, Yasmin H., Rudinskas, Leona C., Rodgers, Angela, Pond, Gregory R., Shepherd, Frances A.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 190 KB

english, 2003

49

Can a computerized format replace a paper form in PRO and HRQL evaluation? Psychometric testing of the computer-assisted LCSS instrument (eLCSS-QL)

Patricia J. Hollen, Richard J. Gralla, John A. Stewart, Jacinta M. Meharchand, Rafal Wierzbicki, Natasha Leighl

Journal:

Supportive Care in Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 193 KB

english, 2013

50

A Phase I Open-Label Dose-Escalation Study of Intravenous BI 2536 Together With Pemetrexed in Previously Treated Patients With Non–Small-Cell Lung Cancer

Peter M. Ellis, Quincy S. Chu, Natasha Leighl, Scott A. Laurie, Holger Fritsch, Birgit Gaschler-Markefski, Steve Gyorffy, Gerd Munzert

Journal:

Clinical Lung Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 389 KB

english, 2013